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As the federal government prepares to launch an ambitious initiative to end the HIV epidemic, the director of the Centers for Disease Control on Friday applauded an Alabama HIV clinic's commitment to providing health services to rural communities. Director Robert Redfield met with state public health officials and toured the Medical Advocacy & Outreach clinic in Montgomery to begin laying the groundwork for the decade-long federal campaign.
Design work for a minimum-size atomic warhead called the XW-51 began at the University of California Radiation Laboratory in the mid 1950s. It later shifted to the Los Alamos Scientific Laboratory, which was also working on compact warheads, and re-designated the W-54 in January 1959. Initially intended to be used for lightweight thermonuclear weapons, the prototype subsequently was adapted for a variety of tactical uses by the armies in the field.XW-51 precursors, as well as compact LASL designs, were first evaluated as part of Operation Plumbbob at the Nevada Test Site in 1957. The most powerful of these Plumbbob prototypes was a boosted, plutonium-cored implosion device that produced a 9.7-kiloton yield. This device incorporated the latest technological advances, prominent among them the powerful, plastic-bonded explosives (PBX) that could be machined into lenses that shaped a perfectly symmetrical shock wave to compress the fissile core to the density needed to sustain an atomic chain reaction. Deuterium-Tritium gas-boosting was also used, a technology first evaluated with a sealed beryllium core during Operation Teapot in 1955. Known as fusion boosting, this process used neutrons from the fusion of a D-T gas mixture blown into a hollow core just before detonation to greatly accelerate the chain reaction.
When you think about rabies, you might consider dogs or raccoons to be the first ones to pass the viral disease, but according to a new report, you’re more likely to get it from bats. Rabies is a deadly virus that, up until 1960, had been spread mainly through domesticated animals like dogs. Once they began getting vaccinated for the disease, however, wild animals became the main rabies hosts, causing about one to three human deaths each year in the United States — a drop from over 100 deaths a year in the early 1900s, according to the Centers for Disease Control and Prevention (CDC).
As part of her role as this year’s honoree for the City of Hope “Spirit of Life” initiative, Sylvia Rhone was feted Friday morning at a lovely (although windy) breakfast gathering on the roof of Sony Music’s headquarters in New York. The initiative raises money for the City of Hope cancer treatment and research center […]
The full moon in Sagittarius is here, and it’s also a Strawberry Moon. The full moon gets a different nickname each month, based on Algonquin naming traditions. The full moons in June is called a Strawberry Moon because it coincides with the strawberry harvest.
A Russian scientific institute says an almost perfectly preserved head of a 32,000-year-old wolf was found in Siberia, so complete that it is still covered with fur and its brain is intact. Scientists from the Republic of Sakha’s Academy of Sciences in Russia's Arctic region of Yakutia, announced the find this week, hailing it as the first of its kind. The head was found by a local man, Pavel Efimov, close to the Tirekhtyakh River in Yakutia in the summer of 2018, according to a press release published on the institute's website.
The bank loaned CrowdStrike Holdings Inc.’s chief executive officer about $10 million to exercise stock options and pay taxes, according to the software-maker’s prospectus. Kurtz pledged as collateral a quarter of his 10% stake in CrowdStrike, whose market value has nearly doubled since Tuesday’s initial public offering, making Kurtz a billionaire.
Pandas are listed as a vulnerable species, but conservation efforts have helped reduce their danger of extinction. The pair, named Hehe (meaning Harmony, pronounced Huh-huh) and Meimei (Happiness, pronounced May-may), were taken out of a dormitory on a bright sunny day this week to gulp milk and munch bamboo in front of some 100 visitors. The birth of Hehe and his younger sister Meimei, on July 25 last year in the Hetaoping panda base , was a success in China's attempt to introduce genes of wild pandas into the captive population.
Advisers for three groups of creditors have held informal discussions with Frontier ahead of $2.7 billion of debt maturities in 2022, according to people with knowledge of the matter. A group including Elliott Management Corp., Apollo Global Management LLC, Franklin Resources Inc. and Capital Group Cos. had proposed swapping their unsecured debt into new secured notes in an out-of-court transaction, with some members also favoring a Chapter 11 bankruptcy filing, the people said.
During a climate change discussion on CBS This Morning on Friday, Rep. Steve Scalise (R-LA) responded to questions about man-made climate change contributing to erosion of land in his home state by claiming Louisiana is using Gulf of Mexico oil drilling revenues to rebuild land, prompting host Tony Dokoupil to hold his feet to the fire.Noting that scientists have found that Lousiana is losing the equivalent of a football field of land to the Gulf of Mexico every hour, Dokoupil asked Scalise if he accepted the science of man-made climate change and, if so, where’s his plan to address it.Scalise, who was making the morning show rounds to hawk his new book, replied that his state’s land loss was mostly due to “coastal erosion” and Dokoupil countered that his own state’s scientists said climate change was “man-made” and sea levels were rising.“We can debate this for hours,” Dokoupil stated. “Scientists have agreed that climate change is a catastrophic risk, do you have a plan, as some other members of your party are beginning to address it?”The House Minority Whip, meanwhile, fell back to one of climate-change deniers’ favorite talking points: the earth’s temperature changes all the time. “So you don’t accept the science?” Dokoupil wondered, causing Scalise to claim scientists said in the 1970s “we were entering a new cooling period.”NASA, however, has shown that the planet’s average temperature has risen nearly two degrees Fahrenheit since the late 19th century and that most of that warming has taken place in the past three decades.As the CBS host pushed back on Scalise’s description of climate change, the Louisiana lawmaker explained that his state was taking oil money to combat the effects on their coast.“Let me tell you what we’re doing—we’re actually taking revenues from drilling in the Gulf of Mexico and using that to rebuild land to rebuild our coast,” he said. “I think it's a real important step to show people how to take ownership of the problem that they have in their own community."For his part, Dokoupil concluded by pointing out how this seemed highly contradictory.“So to save your constituents from climate change, you’re drilling more in the Gulf of Mexico?" Read more at The Daily Beast.Got a tip? Send it to The Daily Beast hereGet our top stories in your inbox every day. Sign up now!Daily Beast Membership: Beast Inside goes deeper on the stories that matter to you. Learn more.
ArQule (NASDAQ:ARQL) began the day and ended the week with a bang as the company's latest blood cancer treatment has shown early signs of promise in helping patients with tumors heal.The Woburn, Mass.-based pharmaceutical business announced its preliminary data from a Phase 1 trial in regards to its investigational cancer drug ARQ 531. The company's early-stage trial is still ongoing, and it examined the effects of several different doses of the drug in 34 patients suffering from advanced chronic lymphocytic leukemia (CLL), small lymphocytic leukemia (SLL), Richter's Transformation, Waldenstrom macroglobulinemia as well as other B-cell Non-Hodgkin lymphomas.ArQule's Phase 1 trials are designed to establish a recommended dose of a new drug for study for the Phase 2 trials. Researchers from the study looking at ARQ 531 said patients were fine at dosages of up to 65 milligrams once a day.InvestorPlace - Stock Market News, Stock Advice & Trading TipsThe drug displayed promising anti-tumor activity in some patients, according to the company. "We are now focused on finalizing the recommended Phase 2 dose and planning for the expansion of our clinical efforts with ARQ 531 into later stage trials across multiple indications as a single agent and as a combination therapy," said ArQule Chief Medical Officer Brian Schwartz in a statement.ARQL stock is soaring a whopping 32.6% following the company's news on Friday. This helped push the company's per share price to a 12-year high of $8.34. More From InvestorPlace * 10 Stocks to Buy That Wall Street Expects to Soar for the Rest of 2019 * 7 Stocks to Buy for the Coming Recession * 7 High-Quality Cheap Stocks to Buy With $10 Compare Brokers The post ArQule News: ARQL Stock Skyrockets on Blood Cancer Study Results appeared first on InvestorPlace.
In the Canadian Arctic, layers of permafrost that scientists expected to remain frozen for at least 70 years have already begun thawing. The once-frozen surface is now sinking and dotted with melt ponds and from above looks a bit like Swiss cheese, satellite images reveal."We were astounded that this system responded so quickly to the higher air temperatures," said Louise Farquharson, a co-author of the study and postdoctoral fellow at the Permafrost Laboratory at the University of Alaska Fairbanks.Permafrost is ground that remains frozen for at least two years. It underlies about 15% of the unglaciated Northern Hemisphere and serves a critical role in the transfer of carbon from living things to the atmosphere, Farquharson said. [Photos: Perfectly Preserved Baby Horse Unearthed in Permafrost]Farquharson is part of an international team of researchers monitoring environmental variables on three islands in the Canadian Arctic. The data they analyzed in this study, which was published Monday (June 10) in the journal Geophysical Research Letters, was gathered between 2003 and 2016.The researchers recorded permafrost thawing to depths that were not expected until air temperatures reached levels the Intergovernmental Panel on Climate Change has predicted will occur after 2090, according to one of its "moderate" climate change models. The IPCC, which is a body of the United Nations, provides scientific information to help guide countries' climate policies.The researchers believe higher summer temperatures, low levels of insulating vegetation and the presence of ground ice near the surface contributed to the exceptionally rapid and deep thawing.The most striking evidence is visible to the naked eye. As upper layers of permafrost thaw and ice melts, the land settles unevenly, forming what is known as thermokarst topography. Landscapes in the Canadian Arctic that had been defined by gently rolling hills are now pockmarked with ditches and small ponds. The ground at the northernmost study site sank by about 35 inches (90 centimeters) over the course of the study."We had this flat terrain when we started monitoring," Farquharson told Live Science. "In 10 or so years, we saw the landscape transform."Their data allowed the researchers to interpret the topographical changes happening before their eyes."We were able to tie together air temperature and ground temperature with the formation of this thermokarst terrain," Farquharson said. Global implicationsThe thawing has climatic implications for the globe and immediate ecological ramifications for the region. Thawing caused by higher air temperatures threatens to exacerbate global climate change."Permafrost is like a giant freezer that contains a lot of really delicious plant material and organics that aren't being decomposed by microbes," Farquharson said. "Thawing opens the freezer door" and allows the microbes to start converting that organic material into CO2.In changing the physical makeup of the landscape, thermokarst also affects local ecosystems and waterways by inviting new plant growth, disrupting stable nutrient cycles and allowing for the sedimentation of streams and possibly coastal systems.Determining the extent of new thermokarst development is difficult, but there is little doubt the problem is widespread. Farquharson and her team guess that about 231,000 square miles (600,000 square kilometers) of permafrost, or about 5.5% of the zone that is permafrost year-round, is vulnerable to rapid surface thawing. * The Reality of Climate Change: 10 Myths Busted * In Photos: The Vanishing Ice of Baffin Island * Images of Melt: Earth's Vanishing IceOriginally published on Live Science.
The innovation has exploded in the skin-care world, and many brands have successfully been able to put the power of acne-fighting ingredients into teeny stickers that put the kibosh on your breakout. To help enhance your emergency acne kit, we rounded up the acne patches Refinery29 staffers swear by, ahead.
“Undeniable” might be a useful descriptor, but let’s frame climate change differently: how this reality manifests itself within the human experience, and how politics are being shaped by that experience. In 2015, the global median age was just below 30, so a changing climate is the only thing most people on Earth have known. Different age groups have contrasting views of a climate of constant change and volatility. A recent Gallup poll separated Americans into three climate change cohorts: "Concerned believers" are highly worried about global warming, think it will pose a serious threat in their lifetime, believe it's the result of human activity, and think news reports about it are accurate or underestimate the problem.
NIH Funding Opportunities
- Notice of Correction to Application and Submission Information for PAR-18-543 "CREATE Bio Development Track: Nonclinical and Early-Phase Clinical Development for Biologics (U44 Clinical Trial Optional)"
- National Institute of General Medical Sciences (NIGMS) Bridges to the Doctorate (T32)
- Notice of Clarification to the Award Budget for PAR-18-894, "Mental Health Research Dissertation Grant to Enhance Workforce Diversity (R36 Independent Clinical Trial Not Allowed)"
- Notice of Intent to Publish a Funding Opportunity Announcement for the NIH Common Fund Acute to Chronic Pain Signatures Program: Multisite Clinical Center Acute Pain from Musculoskeletal Trauma or Acute Peri-operative Pain (UM1 Clinical Trial Optional)
- Notice of Change to the Award Budget for PAR-18-802 "Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings (R41/R42 - Clinical Trial Optional)".