NIH Funding Opportunities

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Weekly Funding Opportunities and Policy Notices from the National Institutes of Health.
Updated: 1 hour 11 min ago

Biology of Bladder Cancer (R01 Clinical Trial Optional)

Mon, 02/04/2019 - 23:45
Funding Opportunity PAR-19-183 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) solicits applications investigating the biology and underlying mechanisms of bladder cancer. Bladder cancer is a significant health problem both in the United States and globally. Because of the high incidence and frequent tumor recurrence, bladder cancer exacts an outsized medical burden. While recent progress has been made in the molecular profiling of bladder cancers and identification of mutated genes, relatively little is known regarding the molecular mechanisms driving initiation, progression, and malignancy of bladder cancer. Furthermore, our understanding of biological processes of the normal bladder at the molecular, cell and organ levels is limited. Fundamental knowledge of how molecular and cellular functions of the bladder are altered in cancer will aid our understanding of bladder cancer biology and interventions. Applications that involve multidisciplinary teams and use clinical specimens or investigate both normal and cancer processes are encouraged.
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Notice to Extend PAR-19-027, "Basic Neurodevelopmental Biology of Circuits and Behavior (R01 Clinical Trial Not Allowed)"

Mon, 02/04/2019 - 06:49
Notice NOT-MH-18-071 from the NIH Guide for Grants and Contracts
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Notice to Extend, PAR-19-028 "Basic Neurodevelopmental Biology of Brian Circuits and Behavior (R21 Clinical Trial Not Allowed)

Mon, 02/04/2019 - 06:41
Notice NOT-MH-18-072 from the NIH Guide for Grants and Contracts
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Refinement and Testing of Interventions to Sustain ADHD Treatment Effects Across Settings and Developmental Transitions (R34 Clinical Trial Required)

Mon, 02/04/2019 - 00:21
Funding Opportunity RFA-MH-20-100 from the NIH Guide for Grants and Contracts. NIMH seeks applications for pilot projects to evaluate the preliminary effectiveness of augmented or modified interventions designed to promote sustained improvement in attention-deficit/hyperactivity disorder (ADHD) symptoms and functional impairments across settings and transitions in children, adolescents, and young adults. An emphasis is placed on trials that go beyond seeking incremental gains in intervention effects, and instead take a theory-driven, empirical approach to applying modifications that will have a significant and enduring impact on functioning. In this pilot phase of effectiveness research, the trial should be designed to evaluate the feasibility, tolerability, acceptability, safety, and potential effectiveness of the approach; to address whether the intervention engages the target mechanism(s) presumed to underlie the intervention effects; and to obtain necessary preliminary data as a pre-requisite to a larger-scale, definitive effectiveness trial.
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Pre-Solicitation Notice: NIAID Clinical Research Products Management Center

Fri, 02/01/2019 - 10:49
Notice NOT-AI-19-039 from the NIH Guide for Grants and Contracts
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