NIH Funding Opportunities

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Weekly Funding Opportunities and Policy Notices from the National Institutes of Health.
Updated: 34 min 44 sec ago

Patient Safety in the Context of Perinatal, Neonatal, and Pediatric Care (R01 - Clinical Trial Optional)

Mon, 05/21/2018 - 08:12
Funding Opportunity PA-18-790 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) encourages a wide range of collaborative research projects related to patient safety in the context of perinatal, neonatal and pediatric care both in routine hospital settings and in intensive care units. The FOA welcomes applications related to (but not limited to): the epidemiology of various domains of medical errors and consequent patient harm; assessing the factors at various levels that contribute to such errors; and intervention strategies at individual, systems, and institutional-levels to help reduce and eliminate medical errors. It is anticipated that knowledge gained from these projects will help develop strategies to deliver highest quality of healthcare to all newborn infants and children with utmost safety and effectiveness.
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Notice of Information: NIMH Council Workgroup on Genomics' Recommendations for Basic and Clinical Research

Fri, 05/18/2018 - 09:18
Notice NOT-MH-18-035 from the NIH Guide for Grants and Contracts
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BRAIN Initiative: Exploratory Team-Research BRAIN Circuit Programs - eTeamBCP (U01 Clinical Trial Not Allowed)

Thu, 05/17/2018 - 08:48
Funding Opportunity RFA-NS-18-029 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to promote the integration of experimental, analytic, and theoretical capabilities for large-scale analysis of neural systems and circuits. This FOA seeks applications for exploratory research studies that use new and emerging methods for large scale recording and manipulation of neural circuits across multiple brain regions. Applications should propose to elucidate the contributions of dynamic circuit activity to a specific behavioral or neural system. Applications should seek to understand circuits of the central nervous system by systematically controlling stimuli and/or behavior while actively recording and/or manipulating relevant dynamic patterns of neural activity and by measuring the resulting behaviors and/or perceptions. Studies should incorporate rich information on cell-types, on circuit functionality and connectivity, and should be performed in conjunction with sophisticated analysis of complex, ethologically relevant behaviors. Applications should propose teams of investigators that seek to cross boundaries of interdisciplinary collaboration by bridging fields and linking theory and data analysis to experimental design. Exploratory studies supported by this FOA are intended to develop experimental capabilities and quantitative, theoretical frameworks in preparation for a future competition for larger-scale, multi-component, Team-Research BRAIN Circuit Programs (U19).
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Cooperative Agreement to Support Regulatory Research Related to the 2018 Prescription Drug User Fee Act and the 21st Century Cures Act (U19)

Thu, 05/17/2018 - 00:05
Funding Opportunity RFA-FD-18-025 from the NIH Guide for Grants and Contracts. The primary objective of this effort is to provide supporting research, identify key issues, and convene appropriate subject matter experts to help inform major initiatives for process improvement and regulatory science related to FDA commitments under the 2018 reauthorization of the Prescription Drug User Fee Act (PDUFA VI) and the 21st Century Cures Act legislation.
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Notice of Legislative Mandates in Effect for FY 2018

Wed, 05/16/2018 - 11:04
Notice NOT-OD-18-181 from the NIH Guide for Grants and Contracts
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Notice of Fiscal Policies in Effect for FY 2018

Wed, 05/16/2018 - 10:56
Notice NOT-OD-18-180 from the NIH Guide for Grants and Contracts
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NIDA to Highlight Topics of Special and/or Continuing Interest in Addiction Research on the NIDA Website

Wed, 05/16/2018 - 10:35
Notice NOT-DA-18-017 from the NIH Guide for Grants and Contracts
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Request for Proposals (RFP) N01CN77019-18 "PREVENT Cancer Preclinical Drug Development Program"

Wed, 05/16/2018 - 10:31
Notice NOT-CA-18-073 from the NIH Guide for Grants and Contracts
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Cardiothoracic Surgical Trials Network (CTSN) Linked Clinical Research Centers (UM1 Clinical Trial Not Allowed )

Wed, 05/16/2018 - 10:19
Funding Opportunity RFA-HL-19-009 from the NIH Guide for Grants and Contracts. The Funding Opportunity Announcement (FOA) invites applications from qualified institutions willing to participate with NHLBI in the Cardiothoracic Surgical Trials Network (CTSN) as Linked Clinical Research Centers (LCRCs). The LCRCs will: (1) conduct collaborative randomized controlled trials (RCTs) and studies that evaluate cross specialty team-based care, interventions and novel therapies in the context of cardiac surgery but with broader relevance to cardiology and neurology; (2) utilize these findings to improve patient outcomes, and influence clinical practice, with benefits that are translatable to the general population; (3) conduct implementation research alongside RCTs to understand the best strategies for optimal uptake and sustainability and to bolster translation in areas of high disease burden; and (4) foster the next generation of clinical and implementation researchers.
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Limited Competition: Cardiothoracic Surgical Trials Network (CTSN) Data Coordinating Center (U01 Clinical Trial Required)

Wed, 05/16/2018 - 10:18
Funding Opportunity RFA-HL-19-010 from the NIH Guide for Grants and Contracts. The limited Funding Opportunity Announcement (FOA) invites an application to support the Data Coordinating Center (DCC) for the Cardiothoracic Surgical Trials Network (CTSN). A separate FOA (RFA-HL-19-009) seeks applications for Linked Clinical Research Centers (LCRCs). The goals of the CTSN renewal are to: (1) conduct collaborative randomized controlled trials (RCTs) and studies that evaluate cross specialty team-based care, interventions and novel therapies in the context of cardiac surgery but with broader relevance to cardiology and neurology; (2) utilize these findings to improve patient outcomes, and influence clinical practice, with benefits that are translatable to the general population; (3) conduct implementation research alongside RCTs to understand the best strategies for optimal uptake and sustainability and to bolster translation in areas of high disease burden; and (4) foster the next generation of clinical and implementation researchers.
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Genetic analysis of non-human animal models to understand the genomic architecture of substance use disorders and addictive behaviors (U01 Clinical Trial Not Allowed)

Wed, 05/16/2018 - 09:17
Funding Opportunity PAR-18-789 from the NIH Guide for Grants and Contracts. The goals of this initiative are to discover allelic variants, genomic alterations, and functional changes associated with addictive behaviors in non-human animals through systems studies that employ genetic and genomics strategies. We also encourage proposals that take genetic and/or genomics approaches to integrate data, delineate gene networks, and uncover the function of known or newly discovered genetic or epigenetic variants.
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Precision Imaging of Oral Lesions (R21-Clinical Trial Not Allowed)

Wed, 05/16/2018 - 08:52
Funding Opportunity PAR-18-788 from the NIH Guide for Grants and Contracts. The intent of this Funding Opportunity Announcement (FOA) is to advance the development, adaptation, optimization, and validation of accurate, reproducible, specific, and sensitive imaging approaches to improve diagnosis, treatment and treatment monitoring for diseases and conditions in the oral cavity and oropharynx.
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Precision Imaging of Oral Lesions (R01- Clinical Trial Not Allowed)

Wed, 05/16/2018 - 08:52
Funding Opportunity PAR-18-787 from the NIH Guide for Grants and Contracts. The intent of this Funding Opportunity Announcement (FOA) is to advance the development, adaptation, optimization, and validation of accurate, reproducible, specific, and sensitive imaging approaches to improve diagnosis, treatment and treatment monitoring for diseases and conditions in the oral cavity and oropharynx.
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Notice of NIDDK Workshop for Biomarkers for the Diabetic Foot Consortium (DFC)

Wed, 05/16/2018 - 08:36
Notice NOT-DK-18-017 from the NIH Guide for Grants and Contracts
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NHLBI SBIR Phase IIB Bridge Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 - Clinical Trial Optional)

Wed, 05/16/2018 - 08:27
Funding Opportunity RFA-HL-19-017 from the NIH Guide for Grants and Contracts. The purpose of the NHLBI SBIR Phase IIB Bridge Award is to facilitate and accelerate the capital-intensive steps that are required to transition SBIR/STTR Phase II projects to the commercialization stage by promoting partnerships between SBIR/STTR Phase II awardees and third-party investors and/or strategic partners. Applicants must submit a Commercialization Plan, which should include details on any independent third-party funding that has already been secured or is anticipated during the Phase IIB Bridge Award project period. It is expected that the level of this independent third-party funding will be equal to or greater than the NHLBI funds being requested throughout the Phase IIB Bridge Award project period. Projects proposed in response to this FOA must relate to the NHLBI mission and require eventual Federal regulatory approval/clearance. Proposed projects may address preclinical and/or clinical stages of technology development. Clinical trials may be proposed as appropriate, but are not required.
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