Science RSS Feeds
British drugmaker AstraZeneca Plc said on Tuesday its cancer drug being jointly developed with U.S.-based Merck & Co met the primary goal in a late-stage study for a rare type of pancreatic cancer. The study showed that Lynparza was successful as a first-line maintenance treatment for adults with a form of genetically-mutated pancreatic cancer called germline BRCA -mutated metastatic adenocarcinoma of the pancreas. Lynparza, which is currently being used as a treatment for ovarian and breast cancers, showed it was better at delaying the rare pancreatic cancer from getting worse in patients when compared to a placebo.
The analysis, published Tuesday by the Berlin-based policy researcher, underscores the challenge climate advocates face entering European Union elections in May, which could challenge the durability of the bloc’s goals amid broad social and economic uncertainty. “Most of the narratives used to counter climate and energy policies are fundamentally rooted in economic or social justice grievances,” according to the report’s authors Stella Schaller and Alexander Carius. Support for right-wing populists looks set to surge in May’s European elections, with parties like Italy’s Northern League and Poland’s Law and Justice likely to gain seats at the expense of established parties.
ZTE’s embarked on a remarkable comeback. The smaller rival to closely held Huawei Technologies Co. became one of the 10 best performers on the MSCI China Index this year after soaring roughly a third over the past week, propelled by growing optimism over its role in next-generation wireless as well as seeming progress in U.S.-Chinese trade talks.
Paying GPs to identify dementia undermines patients’ trust in doctors, a study suggests. In recent years, health officials have introduced a series of schemes which typically pay family doctors £55 a head for every patient classed as having the condition. The initiatives came despite concern from some GPs that they would be seen as “bribes” which could sway doctors towards misdiagnosis. Researchers from the University of York examined more than 7,000 practices in England to examine the impact of the schemes, which began to be introduced in 2013. The study found that the incentives were associated with a significant fall in confidence and trust in the GP – of around five percentage points, in patient polling. Across all practices, around 68 per cent of patients said they had trust and confidence in their doctors. A similar fall was seen in the extent to which patients felt that care was centred around on them, while access to care fell by 3.6 percentage points. A number of GPs objected to the payments system, calling it an “ethical travesty” which amounted to “cash for diagnoses”. The early signs of dementia The new study said the incentives, which were in place from 2013 to 2016, were associated with an increase in diagnosis rates. Previous research has shown that the percentage of dementia sufferers with a diagnosis is estimated to have risen from 52 per cent to 69 per cent over the period. The new study said the schemes were associated with a small but significant increase in quality of clinical care – of around 0.7 per cent – and a 1.3 per cent increase in the number of sufferers given an annual review. But it said the findings suggested the schemes were associated with some negative effects on patient experience, in particular when it came to trust and confidence in GPs. Researchers also called for further research to explore whether such initiatives increase the risk of “gaming” with cases being inappropriately classed as likely dementia. “There are no data to test whether practices assessed cases inappropriately in order to gain financially from the schemes,” the authors warn. Dementia | Read more And they said there was a risk of misdiagosis which could have “truly tragic consequences”, especially if doctors felt pressured into providing an early diagnosis. Two main systems of incentives for dementia diagnosis were introduced across the NHS, reaching participation rates of 98.5 per cent and 76 per cent respectively, the study found. Some individual schemes introduced by parts of the NHS offered GPs as much as £200 per head for diagnosis of dementia. Family doctors are already financially rewarded for carrying a host of medical checks, with a portion of their pay related to tasks such as taking blood pressure, measuring cholesterol and carrying out tests for conditions such as diabetes. But the scheme was the first national initiative to offer doctors financial rewards for diagnosing patients with dementia. It followed pledges by ministers to dramatically improve rates of dementia diagnosis.
The U.S. Securities and Exchange Commission asked a judge Monday to hold Musk in contempt for violating last year’s settlement with the agency, raising a fresh round of regulatory issues for the electric-car maker’s chief executive officer. Musk tweets that he’s considering taking Tesla private, with funding secured, prompting the SEC to begin making inquiries into the truthfulness of his posting. Reports say Tesla received a subpoena from the SEC over Musk’s Aug. 7 tweet, showing intensifying regulatory scrutiny for his communications.
Globest.com recently asked Philippe Houdard, co-founder of Pipeline Workspaces, to discuss the forces behind the growth in flex space in the Sunshine State and what it means for the future of co-working space here.
SINGAPORE / SYDNEY (Reuters) - Oil prices slipped on Tuesday, extending losses of more than 3 percent during the previous session, after U.S. President Donald Trump called on OPEC to ease its efforts to boost the market. International Brent futures were at $64.66 a barrel at 0346 GMT, down 10 cents, or 0.2 percent, from their last close. U.S. West Texas Intermediate (WTI) crude futures were at $55.19 per barrel, down 29 cents, or 0.5 percent.
Amgen Chief Executive Robert Bradway said in a statement that the company was "thankful that the jury weighed the evidence carefully and recognized the validity of Amgen's patents." Regeneron and Sanofi said in a statement they disagreed with aspects of the ruling and would seek to have it overturned. "We will continue to vigorously defend our positions against Amgen's overly broad patent claims," Joseph LaRosa, Regeneron's general counsel, said in the statement. Thousand Oaks, California-based Amgen won a similar verdict in 2016, as well as a court order blocking Praluent sales, but an appeals court set aside the victory and ordered a new trial.
If you suffer from seasonal allergies, you probably know that it's best to be prepared for the start of Spring by getting ahead of your symptoms before they completely wipe you out. So, when can you expect those warmer temperatures to arrive?
The tweet “was intended to recapitulate” a statement from an earnings call 20 days earlier -- and pre-approved by Tesla’s general counsel -- in which Musk predicted Model 3 output “should allow us to get to the 10,000 vehicles a week rate or very close to it by the end of the year,” according to the attorneys’ Feb. 22 letter to the SEC included in court filings Monday. The company’s attorneys stressed that Tesla and Musk take seriously their responsibility under the settlement reached with the SEC last year to review communications about securities issues made through Twitter and other social media. “Although the 7:15 PM EST tweet was not individually pre-approved, Mr. Musk believed that the substance had already been appropriately vetted, pre-approved, and publicly disseminated,” they wrote to the agency.
The company raised $15 million late last month, bringing total financing to around $28 million, co-founder and Chief Executive Officer Patrick Sobalvarro said in an interview. Veo’s proprietary technology uses lidar sensors to create real-time maps of factory work spaces, so that robots can slow or stop completely when human workers get too close. There are more than 2 million industrial robots in operation worldwide, mostly toiling inside metal safety cages.
The more often people log what they eat, the more weight they may lose, according to a new study from researchers at the University of Vermont. “Logging your food intake is one of the best predictors of losing weight and keeping it off,” Dr. Jean Harvey, professor of nutrition at the University of Vermont and the lead author of the study, told ABC News. Approximately 40 percent, or 93.3 million adults in the U.S. are obese, according to the Centers for Disease Control and Prevention.
Canada is talking to its partners about expanding sanctions on the Venezuelan government of President Nicolas Maduro, which is under growing pressure to step down, Foreign Minister Chrystia Freeland said on Monday. "We have put many of the senior leaders in the Maduro regime on our sanctions list. Freeland, speaking on a conference call after the regional Lima Group block met in Bogota to discuss the Venezuelan crisis, did not give details.
Angkor, the ancient capital of the Khmer empire, appears to have suffered a gradual decline rather than a catastrophic collapse, according to a study published on Monday. Archaeologists and historians have long sought to explain the 15th-century abandonment of Angkor, with many attributing it to the 1431 invasion by Thai forces from Ayutthaya. "The historical record is effectively blank for the 15th century at Angkor," said Dan Penny, a member of a team of Australian and Cambodian archaeologists and geographers who took part in the study published in the Proceedings of the National Academy of Sciences (PNAS).
International tech and IT firm Cisco Systems has opened a Co-Innovate Center in Singapore, the Bangkok Post reports on Feb. 25. Cisco CTO Dave Ward reportedly said that the new center — there are 14 worldwide — will help stimulate the development of new technology in the region. The branch in Singapore will purportedly concentrate on cybersecurity, the Internet of Things (IoT) and blockchain technology.
Noting that Zarif was not pictured in any of the coverage of the visit, one online website said "the foreign minister was not informed". Zarif played the lead role in striking the deal under which Iran agreed to curbs on its nuclear program in return for the lifting of international financial sanctions. Assad made his first public visit to Iran since the start of Syria's war in 2011 on Monday, meeting Supreme Leader Ayatollah Ali Khamenei and President Hassan Rouhani.
Mars as we know it today is a dusty, dried-up ball of rock with a little bit of ice here and there, but things were much different a long time ago. Through the various missions undertaken by NASA and the European Space Agency we've known for a while now that Mars once had a whole lot of water on its surface.Now, a new set of images from ESA's Mars Express satellite offers a look at what was once a very wet area of the Red Planet. The photos show a landscape that, aside from the obvious impact craters left over from long ago, is quite similar to natural drainage patterns we see here on Earth.ESA describes what we're seeing in the images:> The topography of this region suggests that water flowed downhill from the north (right in the main colour, topography and 3D images) to the south (left), carving out valleys up to two kilometres across and 200 metres deep as it did so. We see these valleys as they stand today, having undergone significant and heavy erosion since they were formed. This erosion is visible in the form of broken down, smoothed, fragmented and dissected valley rims, especially in the valleys cutting from east to west.The water-carved valleys are very apparent to our eyes, but it's hard for scientists to know where the water initially originated. ESA suggests a number of possibilities, including melting glaciers or even precipitation, but we may never know for sure.The more we find out about ancient Mars the more it sounds like present-day Earth. With flowing water and an atmosphere that might have protected the roots of life, it's entirely possible that Mars once hosted life. We don't yet have the evidence to prove that life existed on the planet, but it might not be long before we have it.
NIH Funding Opportunities
- Notice of NIAAA's Participation in PAR-19-246 "Providing Research Education Experiences to Enhance Diversity in the Next Generation of Substance Abuse and Addiction Scientists (R25 - Clinical Trials Not Allowed)
- Notice of Correction to PAR-19-246 "Providing Research Education Experiences to Enhance Diversity in the Next Generation of Substance Abuse and Addiction Scientists (R25 - Clinical Trials Not Allowed)"
- Notice of Special Interest (NOSI): Understanding Factors in Infancy and Early Childhood (Birth to 24 months) That Influence Obesity Development
- Methods to Improve Reproducibility of Human iPSC Derivation, Growth and Differentiation (SBIR) (R44 Clinical Trial Not Allowed)
- Required Use of the xTRACT System to Prepare Data Tables for Training Grant Research Performance Progress Reports in FY 2020