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The researchers measured their total body obesity using body mass index (BMI), as well as central obesity, or excess belly fat, by measuring the waistline. For example, at age five or six, boys with total obesity had nearly 2.7 times higher odds of starting puberty early before age nine, and those with central obesity had almost 6.4 higher odds.
Now, both McClure and the VC firm he co-founded are taking steps to rebuild themselves, this time without one another.It was 2017, when McClure abruptly resigned from 500 Startups, retreating from the spotlight amid allegations from women that he’d behaved inappropriately. No legal action was taken against McClure or the firm.Today, McClure is working on a second act, albeit a lower-profile one.
The second-largest, second-deadliest Ebola outbreak in history has exceeded 1,000 cases in less than nine months. A total of 1,009 people have reported symptoms of hemorrhagic fever in the Democratic Republic of the Congo's northeastern provinces of North Kivu and Ituri since Aug. 1. Among those cases, 944 have tested positive for Ebola, which causes an often-fatal type of hemorrhagic fever, according to Sunday night's bulletin from the country's health ministry. There have been 629 deaths so far, including 564 people who died from confirmed cases of Ebola.
Naspers chose Euronext Amsterdam to list a business that includes its 31 percent holding in Tencent, as well as investments in Russian internet platform Mail.Ru, German food delivery business Delivery Hero and Indian e-commerce startup Swiggy. The listing, meant to attract international investors, is part of Chief Executive Officer Bob Van Dijk’s effort to reduce the gap between the Cape Town-based company’s market value of about 1.41 trillion rand ($97.9 billion) and its Tencent stake. Naspers has been considering listings other than its primary one in Johannesburg, which some investors have encouraged.
In a telephone interview with Reuters, Gates was optimistic about the global plan to eradicate the paralyzing viral disease, but said Afghanistan's conflict and power struggles hamper progress. "The big issue there is always with the Taliban," said Gates, whose multi-billion dollar philanthropic Bill and Melinda Gates Foundation is one of the biggest funders of the polio eradication campaign. Polio is a virus that spreads in areas with poor sanitation.
In the recommendation to European capitals due to be unveiled on Tuesday, member states will be given several months to report to the EU potential cyber threats to the 5G network in their home markets, according to a person familiar with the matter. The information will then help craft a set of minimum EU-wide standards, the person said, which could include government requirements for telecom operators to ensure certain standards from suppliers.
Son, speaking at the Milken Institute conference in Tokyo, said he was close to striking a deal to acquire 30 percent of the U.S. e-commerce pioneer with Chief Executive Officer Jeff Bezos in its early years. Son offered $100 million, but Bezos insisted on $130 million. "We were laughing about it when I met him again recently,” Son said.
British drugmaker AstraZeneca Plc said on Monday the European Commission approved its diabetes drug Forxiga for use as an oral supplement to insulin in adults with a rare type of the disease. Forxiga can now be used along with insulin in patients with Type-1 diabetes and a Body Mass Index (BMI) of 27 or more when insulin alone has not been able to control blood sugar levels, the company said. Type-1 diabetes is a chronic condition in which the pancreas produces little or no insulin hormone.
The protagonists in a wide-ranging and bitter legal battle before the U.S. International Trade Commission argue that the other’s actions are damaging the nation’s lead in fifth-generation wireless technology. The agency is scheduled to release key decisions on Tuesday in the long-running fight over patent royalties -- including one that could lead to an import ban on one of the U.S. economy’s most iconic products. A ruling from the trade commission favoring Apple could undermine Qualcomm’s attempts to defend its business model and keep on charging billions of dollars in technology licensing fees.
Notice of NHLBI Participation in PA-19-034 "Commercializing Understudied Proteins from the Illuminating the Druggable Genome Project (IDG) (R43/R44 Clinical Trial Not Allowed)"
The Navy has taken several new steps in its development of several large underwater drones designed to conduct undersea reconnaissance, share combat essential data with submarine “motherships,” search for and destroy mines and - in some cases - launch attacks on enemy surface and undersea vessels.
Notice of NHLBI Participation in PA-19-033 "Commercializing Understudied Proteins from the Illuminating the Druggable Genome Project (IDG) (R41/R42 Clinical Trial Not Allowed)"
U.S. sanctions on Venezuela's oil industry have made winners out of Royal Dutch Shell Plc and BP Plc, Gulf of Mexico offshore heavyweights, as refiners in need of substitutes are scooping up oil produced in the region. Trading volumes in these grades of oil have surged to the highest in months, and prices touched five-year peaks after sanctions were imposed.
A trove of Aztec sacrifices including a richly adorned jaguar dressed as a warrior and recently discovered in downtown Mexico City could lead archaeologists to the most tantalizing find yet: an Aztec emperor's tomb. Discovered off the steps of the Aztec's holiest temple during the reign of the empire's most powerful ruler, the sacrificial offerings also include a young boy, dressed to resemble the Aztec war god and solar deity, and a set of flint knives elaborately decorated with mother of pearl and precious stones. The offerings were deposited by Aztec priests over five centuries ago in a circular, ritual platform once located in front of the temple where the earliest historical accounts describe the final resting place of Aztec kings.
The U.S. ride-hailing giant will pay $1.4 billion in cash and $1.7 billion in convertible notes for Careem, the people said, asking not to identified because the talks are private. The notes will be convertible into Uber shares at a price equal to $55 per share, according to the term-sheet seen by Bloomberg. Shareholders in Careem, whose backers include Saudi Prince Alwaleed bin Talal’s investment firm and Japanese e-commerce company Rakuten Inc., have been asked to agree to the terms of the transaction by Monday evening and a deal could be announced as soon as Tuesday, the people said.
"There are legal responsibilities that need to be discussed," Smith, who’s also the software maker’s chief legal officer, wrote in a Sunday blog post that said a company team had begun a pre-planned trip to the country the day before. After video of the killings went viral on social media, some policy-makers urged that these sites take greater responsibility for stemming the spread of violent content. It was not immediately clear how Smith would change policy, although he appeared open to solutions that went beyond industry best practices and self-regulation.
NIH Funding Opportunities
- Notice of Correction to Application and Submission Information for PAR-18-543 "CREATE Bio Development Track: Nonclinical and Early-Phase Clinical Development for Biologics (U44 Clinical Trial Optional)"
- National Institute of General Medical Sciences (NIGMS) Bridges to the Doctorate (T32)
- Notice of Clarification to the Award Budget for PAR-18-894, "Mental Health Research Dissertation Grant to Enhance Workforce Diversity (R36 Independent Clinical Trial Not Allowed)"
- Notice of Intent to Publish a Funding Opportunity Announcement for the NIH Common Fund Acute to Chronic Pain Signatures Program: Multisite Clinical Center Acute Pain from Musculoskeletal Trauma or Acute Peri-operative Pain (UM1 Clinical Trial Optional)
- Notice of Change to the Award Budget for PAR-18-802 "Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings (R41/R42 - Clinical Trial Optional)".