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Funding Opportunity RFA-AI-19-068 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications for the Immune Tolerance Network. The major goal of this Network is to develop tolerogenic approaches for the treatment and prevention of disease in three clinical areas: asthma and allergic diseases; autoimmune diseases; and immune-mediated consequences of allotransplantation. The scope of research to be carried out includes: 1) the design and conduct of clinical trials at all phases to evaluate the safety and efficacy of investigational products and approaches for the induction and maintenance of immune tolerance in humans; 2) the design and conduct of mechanistic studies and the development of tolerance assays as integral components of the clinical trials undertaken, including establishing and directing a consortium of laboratories; and one or more biospecimen repositories, and 3) the provision of bioinformatics, data collection, validation and analysis resources. In addition, on a limited basis, the Network may support focused product development and nonclinical studies (e.g., toxicology, pharmacology, pharmacokinetics, etc.) essential for the subsequent evaluation of promising tolerance induction approaches in humans.

Notice NOT-OD-20-039 from the NIH Guide for Grants and Contracts

More than 50 polar bears have gathered on the edge of a village in Russia's far north, environmentalists and residents said, as weak Arctic ice leaves them unable to roam. The Russian branch of the World Wildlife Fund said climate change was to blame, as unusually warm temperatures prevented coastal ice from forming. The WWF said 56 polar bears had gathered in a one-square-kilometre (0.4-square-mile) area near the village of Ryrkaipy in Chukotka on the northeastern tip of Russia.

British Woman Revived by Doctors After Her Heart Stopped for 6 Hours

Notice NOT-OD-20-020 from the NIH Guide for Grants and Contracts

The honeycomb-like structure, designed by architect Thomas Heatherwick, was recently honored at the World Architecture Festival.

Notice NOT-OD-20-021 from the NIH Guide for Grants and Contracts

Here are the biggest names in tech and YouTube who donated to the TeamTrees cause, including Tesla CEO Elon Musk, PewDiePie, and Jeffree Star.

A study looking at 20 years of emergency room data found that head and neck injuries have been on the rise, with a sharp increase occurring in 2007.

Alaska will soon close a year that is shaping up as its hottest on record, with glaciers in the "Frontier State" melting at record or near-record levels, pouring waters into rising global seas, scientists said after taking fall measurements. Lemon Creek Glacier in Juneau, where records go back to the 1940s, had its second consecutive year of record mass loss, with 3 meters erased from the surface, U.S. Geological Survey glaciologist Louis Sass told Reuters. Melt went all the way up to the summit, said Sass, one of the experts who travel to benchmark glaciers to take measurements in the fall.

Climate activist Greta Thunberg said Friday that calls for real action against climate change are still being “ignored" by political leaders despite their continuous praise of the global environmental youth movement she helped create. The Swedish teen was in Madrid, where United Nations-sponsored talks on climate change are underway, to join fellow young climate activists, representatives of Latin America's indigenous peoples, and thousands of other protesters. Thunberg took part in a huge evening protest march through central Madrid.

Notice NOT-OD-20-041 from the NIH Guide for Grants and Contracts

LIGO can now detect gravitational waves almost every week, thanks to a new instrument that squeezes photons in a vacuum.

And 2019 is on course to be the second- or third-warmest year on record, with 2016 still holding the all-time temperature record.

A fresh SpaceX Falcon 9 rocket launched a recycled robotic Dragon cargo capsule today, carrying 5,700 pounds of supplies, satellites and science to the International Space Station. In contrast with Wednesday's planned launch attempt, which was called off due to excessively high upper-level winds, today's countdown proceeded smoothly to liftoff at 12:29 p.m. ET (9:29 a.m. PT) from Cape Canaveral Air Force Station in Florida. Minutes after launch, the Falcon 9's first stage fell away as planned and flew itself back for touchdown on a drone ship stationed hundreds of miles out in the Atlantic Ocean. SpaceX went with an… Read More

Funding Opportunity RFA-AT-20-003 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications that focus on developing resources by refining and testing key concepts that will advance and further support the study of emotional well-being in the field at large. This infrastructure support will facilitate research networks through meetings, conferences, small-scale pilot research, multidisciplinary cross training (such as intensive workshops, summer institutes, or visiting scholar programs), and information dissemination to foster the growth and development of research in the following priority areas: (1) Ontology and measurement of emotional well-being; (2) Mechanistic research on the role of emotional well-being in health; (3) Biomarkers of emotional well-being; (4) Prevention research (mechanisms-focused intervention development in target populations); (5) Technology and outcome measure development for mechanistic studies; (6) Development and validation of well-being measures.

Notice NOT-DA-20-024 from the NIH Guide for Grants and Contracts

Notice NOT-DA-20-016 from the NIH Guide for Grants and Contracts

Novartis strikes a multiyear deal with AWS to leverage artificial intelligence and data analytics to revamp the steps involved in drug manufacturing.

Notice NOT-RM-20-005 from the NIH Guide for Grants and Contracts