Edward Y Skolnik, M.D.

Dr Skolnik's lab studies the Ca2+-activated K+ channel, KCa3.1, which is required for Ca2+ influx and the subsequent activation of B and T cells. They identified several new signaling molecules that are critical for regulating KCa3.1 channel activity in human CD4+ T cells. These studies have the potential to uncover novel pathways that regulate T cell activation and may identify new mechanisms whereby aberrant activation of these pathways can contribute to autoimmune diseases.

Lab location: 
Skirball Institute, Floor 3
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